VirkonS Leaflet JIM2 - Dolittle Farm

1 Virkon SPOWERFUL BROAD SPECTRUM MULTIPURPOSE VIRUCIDAL DISINFECTANTV irkon S, the premier broad spectrum virucidal veterinarydisinfectant, is recognised by industry and governmentsworldwide as a disinfectant of choice for livestock diseaseprevention and control. Virkon S patented formulation is unique. No otherdisinfectant has the same powerful composition. In terms of efficacy Virkon S has been proven highly effective against 65 strains of virus in over 19 viral families, 400 strainsof bacteria and over 100 strains of fungi. This list of provenefficacy includes the major OIE List A diseases of concern;Avian Influenza (H5N1), Newcastle Disease, Classical SwineFever (Hog Cholera) and Foot and Mouth S versatility provides the flexible solution for; surface,water and aerial disinfection, in hard water, on porous surfaces,at low temperatures and in the presence of organic patented formulationEffective against a broad spectrum of disease causing pathogens Highly versatile surface, equipment, water and aerial disinfectionVirkonS Leaflet_JIM2 2/27/06 11:38 AM Page 4 Virkon SVirkon S combines greater application flexibility and broad spectrum activitywith efficacy against viruses, bacteria and fungi at low temperatures, in hard water, on porous surfaces and against organic of ActionVirkon S oxidizes sulphur bonds in proteins and enzymes disrupting the functionof the cell membrane causing rupturing of the cell wall.

2 There is no evidence to suggest that bacterial disease causing organisms developresistance towards Virkon S as opposed to other disinfectant S is meticulously controlled during the manufacture process to be abalanced, stabilized blend of peroxygen compounds, surfactant, organic acids and an inorganic buffer , Health and Environmental IssuesEnvironmental ProfileVirkon S is an oxygen based disinfectant chemistry containing simple organicsalts and organic acids. The active ingredient in Virkon S, decomposes by a variety of routes within the environment, in soil and water, breaking down to form the harmless substances, potassium salts and of the ingredients of Virkon S are inorganic, which decompose in the physical environment to naturally occurring simple inorganic salts. Theremaining, organic components, are classified as readily biodegradable accordingto standard OECD and EU S is not classified as R53, persistent in the environment, according to the standard European process for the classification and labelling of studies have shown that diluted Virkon S should not, when used as directed, pose any threat to sewage treatment SafetyThe results of independent studies carried out in accordance with OECD and EU guidelines indicated that Virkon S powder concentrate does not displayeffects of acute toxicity by exposure to skin or by ingestion.

3 As a result Virkon Sis not classified as harmful or toxic according to the standard European processfor the classification and labelling of chemical tested in accordance with OECD and EU test guidelines a 1%, in-usedilution, of Virkon S does not cause irritation to eyes or skin. Virkon S, powder and in-use dilution (1%) does not cause effects of sensitisationwhen tested to OECD and EU Properties UK DEFRA Approved- Foot and Mouth Disease, Swine Vesicular Disease,Diseases of Poultry and General Orders Powerful- independently proveneffective against viral, bacterial andfungal disease causing organismsincluding the lethal H5N1 AvianInfluenza Virus. Fast-acting- a one percent solution of Virkon S is independently proven to kill bacteria with contact times as low as five minutes and the tough to kill parvovirus in ten minutes or less. Versatile- surface, equipment,vehicle, footdip, water delivery system and aerial disinfection.

4 Independently proven effectiveonporous surfaces, in hard water, at lowtemperatures and in the presence oforganic challenge. Readily soluble in tap water, Virkon Sdissolves into a pink solution. An environmentally acceptableproductwith an exceptional safetyprofiletowards man and animalswhen used and disposed of asinstructed on the label. Transport and storage- being apowdered disinfectant formulationVirkon S can be swiftly transported by air and can be stored for longperiods making it the ideal choice for stockpiling in Leaflet_JIM2 2/27/06 11:38 AM Page 5 Equipment DisinfectionRoutine cleaning anddisinfection of movableequipmentDilution Rate1:100 (10 grams ofVirkon S to every 1 litre of water)ApplicationSpray all equipment with Virkon S solution at anapplication rate of 300ml/m2 Disinfection Foot & WheeldipsDisinfection Foot & WheeldipsDilution Rate1:100 (10 grams ofVirkon S to every 1 litre of water)ApplicationReplace solution once it has either become soiledor after a period of 4-5 days.

5 The dilution of thedisinfectant solution can be checked for potency at the time of preparation using a Virkon S dilution test DisinfectionThe level of disease causing organismspresent after basic cleaning can remain high enough to offer a serious diseasechallenge to livestock. Using adisinfectant proven to be effective against viruses, bacteria, fungi andmoulds, such as Virkon S, is Application Usage ChartTo estimate the total surface area to be disinfected, including walls and ceilings, multiply the total floor area by DisinfectionDisinfectant Footdips and WheeldipsSurface DisinfectionRoutine disinfection for allsurfaces, earth, wood andconcreteDilution Rate1:100 (10 grams ofVirkon S to every 1 litre of water)ApplicationUsing a pressure washer or other mechanicalsprayer, apply Virkon S solution at an applicationrate of 300ml/m2 Surface area to be disinfected50m2100m2500m21000m22500m2 Total volume ofVirkon S solution15 litres30 litres150 litres300 litres750 litres1 :280UK DEFRA Diseasesof Poultry.

6 120UK DEFRA General S has a unique formulation, broad spectrum of activity and exceptional safety profile towards man and animals, when used as directed, making it the disinfectant choice for; general surface, equipment, vehicle, footdip, water deliverysystem and aerial Leaflet_JIM2 2/27/06 11:38 AM Page 6 Water System Disinfection All water systems can potentially contain some viral and bacterial contamination, especially header tanks where dust and debris can accumulate. Disinfection will clean the system and eliminate viruses, bacteria and fungal Disinfection To control organisms that can be introduced into a livestock house or farm building during the setting up procedure, and to disinfect the air and other inaccessible areas of the building, use either a fine mist sprayer or thermal fogging machine to apply Virkon S disinfectant solution System DisinfectionTerminal DisinfectionContinuous Disinfection Dilution Rate1:200 1:100( 1%)1:1000 ( )ApplicationIsolate header tank at the mains and drain off todrinker points farthest from tank.

7 Clean out anygross soiling and debris. Refill with water andadd the appropriate volume of Virkon S powder,thoroughly stir and leave for 10 minutes. Flushsystem through to all drain-off points and leavefor a further 50 minutes before draining systemand refilling with clean header tank as required or apply throughwater system dosing equipment. Aerial DisinfectionMisting/Aerial SprayCold Fogging Thermal Fogging Dilution Rate1:200 ( )1:100 (1%)1:25 (4%) solution ofVirkon S in an 85:15water Virkon S FogEnhancer either a pressure washer or knapsacksprayer on its finest mist setting and apply at 1 litreof Virkon S solution per 10m2of floor a mechanical mister to apply the Virkon Ssolution at a rate of 1 litre per 10m2of floor spaceUsing a thermal fogging machine apply theprepared solution at 1 litre per 40m2of floor spaceFloor spaceof building50m2100m2500m21000m2 Misting / Aerial Spray1:20025g50g250g500gCold Fogging1:10050g100g500g1kgThermal Fogging1:2550g100g500g1kgAerial Disinfection in the Presence of LivestockSpraying a fine disinfectant mist or fog in premises, even in the presence of livestock can help reduce cross infection andsecondary infection during outbreaks of respiratory and other diseases.

8 Using a mechanical or plumbed in misting system, or a pressure washer to deliver a very fine mist, apply Virkon S at a dilution rate of 1:200 and at an application rate of 1 litre per 10m2of floor space two to four times of water tobe disinfected100 litres250 litres500 litres1000 litresTerminal Cleanout1:200 1:100500g 5kg5kg 10kgContinuous Water Disinfection 1:1000100g250g500g1kgVirkon S - Water System Disinfection Usage ChartAerial Disinfection Application Usage ChartVirkonS Leaflet_JIM2 2/27/06 11:38 AM Page 7 Virucidal Activityover 100 independent studiesVirus FamilyAdenoviridaeArenaviridaeAsfarvirid aeAstroviridaeBirnaviridaeBunyaviridaeCa liciviridaeCircoviridaeCoronaviridaeHepa dnaviridaeHerpesviridaeOrthomyxoviridaeP apillomaviridaeParamyxoviridaeParvovirid aePicornaviridaePolyomaviridaePoxviridae ReoviridaeRetroviridaeRhabdoviridaeTogav iridaePoultry Disease/DilutionEgg drop syndrome - 1:100 Poultry enteritismortality syndrome - 1:67 Infectious bursal disease -1:250 Chicken anaemia - 1:250 Infectious bronchitis - 1:100 Marek s disease - 1:200 TRT - 1:200 ILT - 1:100 Avian influenza - 1:280 Newcastle disease - 1:280 Fowl pox - 1:100 Avian reovirus - 1:100 Myeloid leucosis - 1:200 Pig Disease/DilutionAfrican swine fever - 1:800 PMWS/PDNS - 1:100 TGE - 1:100 Aujesky s disease - 1:100 FMD - 1:1300 SVD - 1:200 PRRS - 1:700, CSF/HogCholera - 1.

9 150 Other Disease/DilutionInfectious canine hepatitis -1:100 Lassa fever - 1:200 Infectious pancreaticnecrosis - 1:100 Rift valley fever - 1:400 Feline calicivirus - 1:100 Feline infectious peritonitis -1:100 Hepatitis B-1:100 Equine herpes - 1:100 Infectious bovinerhinotracheitis - 1:600 Equine influenza - 1:100 Bovine papillomatosis - 1:100 Canine parainfluenza - 1:100 ISA - 1:200 Canine parvoviral enteritis -1:100 Polio - 1:100 Bovine polyoma - 1:100 Pseudocowpox - 1:300,Cowpox - 1:100 Rotaviral enteritis - 1:100 Maedi visna - 1:1400 Rabies - 1:600 BVD - 1:100 Equine viral arteritis - 1:100 Bactericidal Activityover 400 independent studiesAgent TestedActinobacilluspleuropneumoniaeBaci llus cereusBordetella aviumBordetella bronchisepticaBrucella abortusCampylobacter coliCampylobacter jejuniCampylobacter pyloridis Chlamydophila psittaciClostridium perfringensDermatophilus congolensisEnterobacter cloacaeErysipelothrix rhusiopathiaeEscherichia coli O157:H7 Eubacterium suisHaemophilus somnusKlebsiella pneumoniaeKlebsiella oxytocaLawsonia intracellularisListeria monocytogenesMycoplasma gallisepticumMycoplasma hyorhinisMycoplasma mycoidesDilution1:2001:1001:1001:1501:10 01:1001:1001:1001:1001:1001:1001:2001:10 01:1001:2001:1001:2001:1001:1001:1001:10 01:8001.

10 200 Agent TestedOrnithobacterium rhinotrachealePasteurella haemolyticaPasteurella multocidaProteus sppPseudomonas aeruginosaPseudomonas malleiSalmonella arizonaSalmonella choleraesuisSalmonella enteritidis PT4 Salmonella thomasvilleSalmonella typhimurium DT104 Serpulina hyodysenteriaeSerratia marcescensShigella sonneiStaphylococcus aureusStaphylococcus epidermidis Staphylococcus intermediusStreptococcus equiStreptococcus faecalisStreptococcus suisStreptococcus zooepidemicusTaylorella (Haemophilus)equigenitalisDilution1:1001 :1001:1501:2001:1001:2001:1001:1201:1001 :2001:2001:4001:2001:1001:1001:1001:1001 :1001:1001:1501:1001:400 The Premier Broad Spectrum Veterinary Livestock DisinfectantThe tables below summarise independent efficacy data for important livestock pathogens. For a complete list, including horticulture and aquaculture pathogens, please see our website Dilutions do not necessarily represent the lowest effective concentration of Virkon S.