Volume 31, Issue 10 April 1, 2013 JOURNAL …

1 Volume 31, Issue 10 April 1, 2013 . JOURNAL OF. CLINICAL. ONCOLOGY. Of cial JOURNAL of the American Society of Clinical Oncology Oncology Grand Rounds: Acute Myeloid Leukemia in First Remission: To Choose Transplantation or Not? Stone Comments and Controversies: Multiplex Genetic Testing for Cancer Susceptibility: Out on the High Wire Without a Net? Domchek et al Effects of Melatonin on Appetite and Other Symptoms in Patients With Advanced Cancer and Cachexia. E. Del Fabbro et al. Editorial: Baracos Effect of Ruxolitinib Therapy on Myelo brosis-Related Symptoms and Other Patient-Reported Outcomes in COMFORT-I. Mesa et al Curability of Patients With Acute Myeloid Leukemia Who Did Not Undergo Transplantation in First Remission. Burnett et al Editorial: Schiffer Implementation of Universal MSI and IHC Screening for Diagnosing Lynch Syndrome in a Large Academic Medical Center. B. Heald et al Lack of Speci city of Plasma Concentrations of Inhibin B and Follicle- Stimulating Hormone for Identi cation of Azoospermic Survivors of Childhood Cancer.

2 Green et al ASCO Special Article: Central Venous Catheter Care for the Patient With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Schiffer et al Volume 31, Issue 10 April 1, 2013 . JOURNAL OF Of cial JOURNAL of the American Society of Clinical Oncology CLINICAL. ONCOLOGY. CONTENTS. EDITORIALS. Clinical Trials of Cancer Cachexia Therapy, Now and Hereafter Vickie E. Baracos (see article on page 1271) .. 1257. If at First You Don't Succeed: Stem-Cell Transplantation for Acute Myeloid Leukemia After First Relapse Charles A. Schiffer (see article on page 1293) .. 1259. ONCOLOGY GRAND ROUNDS. Acute Myeloid Leukemia in First Remission: To Choose Transplantation or Not? Richard M. Stone (see article on page 1293) .. 1262. COMMENTS AND CONTROVERSIES. Multiplex Genetic Testing for Cancer Susceptibility: Out on the High Wire Without a Net? Susan M. Domchek, Angela Bradbury, Judy E. Garber, et al.

3 1267. ORIGINAL REPORTS. Palliative and Supportive Care Effects of Melatonin on Appetite and Other Symptoms in Patients With Advanced Cancer and Cachexia: A Double-Blind Placebo-Controlled Trial Egidio Del Fabbro, Rony Dev, David Hui, et al (see editorial on page 1257) .. 1271. continued on following page JOURNAL of Clinical Oncology (ISSN 0732-183X) is published 36 times a year, three times monthly, by the American Society of Clinical Oncology, 2318 Mill Road, Suite 800, Alexandria, VA 22314. Periodicals postage is paid at Alexandria, VA, and at additional mailing of ces. Publication Mail Agreement Number 863289. Editorial correspondence should be addressed to Stephen A. Cannistra, MD, JOURNAL of Clinical Oncology, 2318 Mill Road, Suite 800, Alexandria, VA 22314. Phone: 703-797-1900; Fax: 703-684-8720. E-mail: Internet: POSTMASTER: ASCO members should send changes of address to American Society of Clinical Oncology, 2318 Mill Road, Suite 800, Alexandria, VA 22314.

4 Nonmembers should send changes of address to JOURNAL of Clinical Oncology Customer Service, 2318 Mill Road, Suite 800, Alexandria, VA 22314. 2013 annual subscription rates, effective September 1, 2012: United States and possessions: individual, $578 one year, $1,098 two years; single Issue , $40. International: individual, $802 one year, $1,524 two years; single Issue , $50. Institutions: bundled (print online): Tier 1: $899 US, $1,248 Int'l; Tier 2: $1,052 US, $1,395 Int'l; Tier 3: $1,519. US, $1,849 Int'l; Tier 4: contact JCO for quote. Institutions: online only, worldwide: Tier 1, $769; Tier 2: $897; Tier 3, $1,295; Tier 4: contact JCO for quote. See for descriptions of each tier. Student and resident: United States and possessions: $289; all other countries, $401. To receive student/resident rate, orders must be accompanied by name of af liated institution, date of term, and the signature of program/residency coordinator on institution letterhead.

5 Orders will be billed at individual rate until proof of status is received. Current prices are in effect for back volumes and back issues. Back issues sold in conjunction with a subscription rate are on a prorated basis. Subscriptions are accepted on a 12-month basis. Prices are subject to change without notice. Single issues, both current and back, exist in limited quantities and are offered for sale subject to availability. JCO Legacy Archive (electronic back issues from January 1983 through December 1998) is also available; please inquire. Volume 31, Issue 10 April 1, 2013 .. Sex Differences in the Return-to-Work Process of Cancer Survivors 2 Years After Diagnosis: Results From a Large French Population-Based Sample Patricia Marino, Luis Sagaon Teyssier, Laetitia Malavolti, et al .. 1277. Effect of Ruxolitinib Therapy on Myelo brosis-Related Symptoms and Other Patient-Reported Outcomes in COMFORT-I: A Randomized, Double-Blind, Placebo-Controlled Trial Ruben A.

6 Mesa, Jason Gotlib, Vikas Gupta, et al .. 1285. Hematologic Malignancies Curability of Patients With Acute Myeloid Leukemia Who Did Not Undergo Transplantation in First Remission Alan K. Burnett, Anthony Goldstone, Robert K. Hills, et al (see editorial on page 1259 and article on page 1262) .. 1293. Post-Transplantation Lymphoproliferative Disorder After Kidney Transplantation: Report of a Nationwide French Registry and the Development of a New Prognostic Score Sophie Caillard, Raphael Porcher, Franc ois Provot, et al .. 1302. T-Cell Replete HLA-Haploidentical Hematopoietic Transplantation for Hematologic Malignancies Using Post-Transplantation Cyclophosphamide Results in Outcomes Equivalent to Those of Contemporaneous HLA-Matched Related and Unrelated Donor Transplantation Asad Bashey, Xu Zhang, Connie A. Sizemore, et al .. 1310. Cancer Prevention and Control Two-Year Randomized Controlled Prospective Trial Converting Treatment of Stable Renal Transplant Recipients With Cutaneous Invasive Squamous Cell Carcinomas to Sirolimus Judith M.

7 Hoogendijk-van den Akker, Paul N. Harden, Andries J. Hoitsma, et al .. 1317. Pediatric Oncology Lack of Speci city of Plasma Concentrations of Inhibin B and Follicle-Stimulating Hormone for Identi cation of Azoospermic Survivors of Childhood Cancer: A Report From the St Jude Lifetime Cohort Study Daniel M. Green, Liang Zhu, Nan Zhang, et al .. 1324. Speci city of Problem-Solving Skills Training in Mothers of Children Newly Diagnosed With Cancer: Results of a Multisite Randomized Clinical Trial Olle Jane Z. Sahler, Michael J. Dolgin, Sean Phipps, et al .. 1329. Gastrointestinal Cancer Implementation of Universal Microsatellite Instability and Immunohistochemistry Screening for Diagnosing Lynch Syndrome in a Large Academic Medical Center Brandie Heald, Thomas Plesec, Xiuli Liu, et al .. 1336. Fluorouracil, Leucovorin, and Irinotecan Plus Either Sunitinib or Placebo in Metastatic Colorectal Cancer: A Randomized, Phase III Trial Alfredo Carrato, Anna Swieboda-Sadlej, Marzanna Staszewska-Skurczynska, et al.

8 1341. Histomolecular Phenotypes and Outcome in Adenocarcinoma of the Ampulla of Vater David K. Chang, Nigel B. Jamieson, Amber L. Johns, et al .. 1348. continued on following page Volume 31, Issue 10 April 1, 2013 .. ASCO SPECIAL ARTICLE. Central Venous Catheter Care for the Patient With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Charles A. Schiffer, Pamela B. Mangu, James C. Wade, et al .. 1357. ART OF ONCOLOGY. Peers Karen C. Daily .. 1371. CORRESPONDENCE. Ketamine and Cancer Pain: The Reports of My Death Have Been Greatly Exaggerated Kate Jackson, Michael Franco, Leeroy William, et al .. 1373. Ketamine in the Management of Cancer Pain Wojciech Leppert .. 1374. Reply to K. Jackson et al and W. Leppert Janet Hardy, Steve Quinn, Belinda Fazekas, et al .. 1375. Research on Chemotherapy-Induced Nausea: Back to the Past for an Unmet Need? Luigi Celio and Matti Aapro .. 1376. Antipsychotics-Containing Regimen As an Alternative to Standard Antiemetics for Delayed Nausea Induced by Highly Emetogenic Chemotherapy Hiroshi Ishiguro, Kosuke Kawaguchi, Tomomi Nishimura, et al.

9 1377. Reply to L. Celio et al and H. Ishiguro et al Joseph A. Roscoe and Charles E. Heckler .. 1378. Dexrazoxane Prevention of Anthracycline Cardiomyopathy Rudolf Steiner and Kurt Hellmann .. 1379. Reply to R. Steiner et al Daniel Lenihan and Daniela Cardinale .. 1380. DIAGNOSIS IN ONCOLOGY. (articles available online). Malignant In ammatory Myo broblastic Tumor of the Prostate Caigang Liu, Xinhan Zhao, Zuowei Zhao, et al .. e144. Diffuse Large B-Cell Lymphoma Associated With Chronic In ammation in Metallic Implant Blanca Sanchez-Gonzalez, Mar Garcia, Ferran Montserrat, et al .. e148. -Fetoprotein Secreting Extrapulmonary Small-Cell Carcinoma of the Liver Mark A. Walshauser, Kazusa Ishii, Kadhir Murugappan, et al .. e152. In ammatory Myo broblastic Tumor of the Colon Simona Gurzu, Tivadar Bara, and Ioan Jung .. e155. continued on following page Volume 31, Issue 10 April 1, 2013 .. Brainstem Ganglioglioma Successfully Treated With Vemurafenib Sarah Rush, Nicholas Foreman, and Arthur Liu.

10 E159. Activating Germline R776H Mutation in the Epidermal Growth Factor Receptor Associated With Lung Cancer With Squamous Differentiation Jan van Noesel, Ward H. van der Ven, Theo van Os, et al .. e161. Cytochrome P17 Inhibition With Ketoconazole As Treatment for Advanced Granulosa Cell Ovarian Tumor Jesus Garcia-Donas, Alicia Hurtado, Zaida Garcia-Casado, et al .. e165. Pulmonary Fibrosis After Pegylated Liposomal Doxorubicin in a Patient With Uterine Papillary Serous Carcinoma Nicole S. Nevadunsky, Chinyere Mbagwu, Nina Mizrahi, et al .. e167. Also in This Issue Supplementary Information Available Information for Subscribers Information for Contributors Manuscript Submission Checklist Current Abstracts Forthcoming Reports JOURNAL OF CLINICAL ONCOLOGY.. Of cial JOURNAL of the American Society of Clinical Oncology EDITOR ROSTER. EDITOR-IN-CHIEF Peter H. Wiernik, MD Diagnosis in Oncology Stephen A. Cannistra, MD, Boston, MA.