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<精神・神経 WG - mhlw.go.jp

WG WG 217 1 80 9 114 17 186 21 250 25 262 31 297 41 305 47 332 51 355 61 3 - 3

精神・神経wg 精神・神経用薬分野 『医療上の必要性の高い未承認薬・適応外薬検討会議』 「医療上の必要性に係る基準」への該当性の評価

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Transcription of <精神・神経 WG - mhlw.go.jp

1 WG WG 217 1 80 9 114 17 186 21 250 25 262 31 297 41 305 47 332 51 355 61 3 - 3 181 71 29 77 89 49 97

2 98 103 113 109 115 119 116 125 172 129 214 135 233 139 236 149 268 153 303 159 324 173 325 179 326 187 WG WG 1 1) 217 2) Hydromorphone Hydrochloride Palladone, Dillaudid, Dillaudid-HP 3)

3 Dilaudid DILAUDID mL 2 10 mL mg 10 mg 3 6 Dilaudid DILAUDID 2 4mg 4 6 DILAUDID DILAUDID 1 2 mg 4 6 1 WG 2 3 DILAUDID DILAUDID DILAUDID-HP DILAUDID-HP DILAUDID-HP DILAUDID DILAUDID-HP

4 DILAUDID DILAUDID-HP DILAUDID-HP 2 WG 12 PALLADONE SR 12 Hydromorphone 4mg 30 mg PALLADONE SR 4 mg 12 Hydromorphone PALLADONE SR 12 12 3 WG 12

5 4mg 30mg 7 15 24 48 4) 1 4 WG 2 QOL 5) 2 6) 7) 3 8)

6 1 2 1 2-5) QOL 1 6) QOL 5 WG 1) Oxford Textbook of Palliative Medicine, Fourth Edition, Oxford University Press (UK), 2010 2) L. Jost and F. Roila: Management of cancer pain: ESMO (European Society for Medical Oncology) Clinical Practice Guidelines.

7 Ann Oncol 21 (Suppl 5): v257-v260, 2010 3) NCCN (National Comprehensive Cancer Network) Clinical Practice Guidelines in OncologyTM, Adult Cancer Pain, 4) GW Hanks et al. Morphine and alternative opioids in cancer pain: the EAPC (European Association for Palliative Care) recommendations. Expert Working Group of the Research Network of the European Association for Palliative Care. Br J Cancer. 84(5):587-93, 2001 5) The management of chronic pain in patients with breast cancer. The Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer.

8 CMAJ. 10; 158: S71-81, 1998 6) Opioids and the Management of Chronic Severe Pain in the Elderly: Consensus Statement of an International Expert Panel with Focus on the Six Clinically Most Often Used World Health Organization step III Opioids (Buprenorphine, Fentanyl, Hydromorphohne, Methadone, Morphine, Oxycodone) Pain Practice, 8(4), 287-313, 2008 9) 10) 11) 6 WG 4 WG 12)

9 WG 1 2 13) 7 8 WG 1 1) 80 2) 3) 5-15mg 4-6 Combined salt 6 12 Combined salt 6 6-12 Combined salt 6 18 12 10mg 9 WG 1 12 2

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