White Paper : 灌流指標 (Perfusion Index)

1 White Paper : ( perfusion Index) Clinical Application of perfusion index PI PI PI PI PI PI PI PI PI

2 PI PI PI PI PI PI 1 White Paper : ( perfusion index ) 940nm 1 PI Masimo SET PI SaO2 SET PI SET PI PI PI PI PI PI 2 PI SaO2

3 PI PI PI PI PI PI CO 2 White Paper : ( perfusion index ) 3 PI Masimo SET 4 PI R= ,p< R=.

4 P= PI R= PI Masimo SET PI 5 p= PI PI p< PI PI 16 Masimo SET PI 6 PI L2 3 L3 4 20 5 PI p< 5 min vs.

5 Paired t-test 20 p< 20 vs. 5 min PI 3 White Paper : ( perfusion index ) PI PI PI 7 40 L2/3 Masimo SET Radical PI 5 PI PI PI 5 p< 1 PI 1 PI PI PI 1 7 4 White Paper .

6 ( perfusion Index) PI 8 PI 101 9 Masimo SET Radical SpO2 43 58 SNAPII score 2 PI vs. , p< SpO2 vs. , p< 139 16bpm vs. 133 17bpm, p< PI PI PI HCA HCA NIRS PI 1 5 43 NIRS PI 4 10 PI p= VO2 PI PI NICU 11

7 PI PI 5 White Paper : ( perfusion index ) PI PI PI PI PI PI PI PI PI Masimo SET PI PI PI PI Goldman JM, Petterson MT, Kopotic RJ, Barker SJ.

8 Masimo signal extraction pulse oximetry. J Clin Monit Comput. 2000; 16:475-483. Hales JR, Stephens FR, Fawcett AA, et al. Observations on a new non-invasive monitor of skin blood flow. Clin Exp Phamacol Physiol. 1989; 16:403-415. Matsukawa T, Kurz A, Sessler DI, Bjorksten AR, Merrifield B, Cheng C. Propofol linearly reduces the vasoconstriction and shivering thresholds. Anesthesiology. 2003; 99:A593. Hager H, Reddy D, Kurz A. perfusion index -a valuable tool to assess changes in peripheral perfusion caused by sevoflurane? Anesthesiology. 2003; 99:A593. Hager H, Church S, Mandadi G, Pulley D, Kurz A. The perfusion index measured by a pulse oximeter indicates pain stimuli in anesthetized volunteers.

9 Anesthesiology. 2004; 101:A514. Kakazu CZ, Chen BJ, Kwan WF. Masimo set technology using perfusion index is a sensitive indicator for epidural onset. Anesthesiology. 2005; 103:A576. Uemura A, Yagihara M, Miyabe M. Pulse oximeter perfusion index as a predictor for the effect of pediatric epidural block. Anesthesiology. 2006; 105:A1354. Genzel-Boroviczeny O, Strotgen J, Harris AG, Messmer K, Christ F. Orthogonal polarization spectral imaging (OPS): a novel method to measure the microcirculation in term and preterm infants transcutaneously. Pediatr Res. 2002; 6 White Paper : ( perfusion Index) 51:386-391. De Felice C, Latini G, Vacca P, Kopotic RJ. The pulse oximeter perfusion index as a predictor for high illness severity in neonates.

10 Eur J Pediatr. 2002; 161:561-562. Zaramella P, Freato F, Quaresima V, et al. Foot pulse oximeter perfusion index correlates with calf muscle perfusion measured by near-infrared spectroscopy in healthy neonates. J Perinatol. 2005; 25:417-422. Baker SJ. Quoted by: Douglas E. perfusion index used as a tool to confirm epidural placement. [Unpublished Paper ] 7