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METHOD 8327

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SW-846 Update VII 8327- 1 Revision 0 July 2021 METHOD 8327 PER- AND POLYFLUOROALKYL SUBSTANCES (PFAS) BY LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY (LC/MS/MS) TABLE OF CONTENTS SCOPE AND 2 SUMMARY OF METHOD ........................................ ........................................ ... 5 DEFINITIONS ........................................ ........................................ .................... 5 INTERFERENCES ........................................ ........................................ ............. 5 SAFETY ........................................ ........................................ ............................. 7 EQUIPMENT AND SUPPLIES ........................................ .................................... 7 REAGENTS AND STANDARDS ........................................ ................................. 9 SAMPLE COLLECTION, PRESERVATION, AND STORAGE ............................ 13 QUALITY CONTROL.

2.1 Samples are prepared using an appropriate sample preparation method (e.g., solvent dilution or extraction). Prepared samples or extracts are then analyzed by LC/MS/MS using external standard calibration. 2.2 Target compounds are qualitatively identified …

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