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Scale-down Model Qualification anddown Model Qualification ...

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Scale-down Model Qualification andScaledown Model Qualification and Use in Process CharacterizationNathan McKnightCMC Strategy Forum28 January, 2013Slide 2Outline Introduction and context Scale-down Model design and key elements Uses and data interpretation Qualification Mitigating uncertainties from Scale-down Model useMitigating uncertainties from scaledown Model use Summary and conclusionsSlide 3Introduction Small-scale models can be developed and used to support process development studies. The development of a Model should account for scale effects and be representative of the proposed commercial process.

Scale-down Model Design: Design Basis Options Slide 5 • By definition, a scale-down model is an incomplete representation of a more complicated, expensive and/or physically larger system.

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