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Appendix I -Intravenous (IV) TO Oral (PO) Dose Conversion ...
albertahealthservices.caconsidered when performing opioid dose conversions. Equianalgesic doses are based on single dose studies and lower doses may be required with repeated administration. For patients on chronic opioid therapy, reduce the calculated dose of the new opioid by 25% to 50% for incomplete cross tolerance.