B-Cell Development, Activation, and Differentiation

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Nov 13, 2014 · B cell activation • Two major types: T cell dependent (TD) and T cell independent (TI) • TD: involves protein antigens and CD4+ helper T cells – 1) Multivalent antigen binds and crosslinks membrane Ig receptors – 2) Activated T cell binds B cell thru antigen receptor and via CD40L (T)/CD40 (B) interaction

  Development, Cells, Activation, Differentiation, T cell, Cell development, And differentiation, Cell activation