Search results with tag "Thalidomide"
Velcade®, thalidomide and dexamethasone (VTD) and …
www.myeloma.org.ukVelcade can be given either through an infusion into a vein or by a small injection under the skin. Injecting Velcade under the skin has become much more popular since it was found to reduce a common side-eff ect of Velcade. What side-eff ects can it cause? Fatigue, painful tingling or numbness in the hands and feet, nausea
Basic Overview of Preclinical Toxicology in Drug Development
www.uab.edu•Thalidomide tragedy (1961-1962) •One of the greatest of all drug disasters •Introduced as safe and effective during pregnancy to treat nausea •Potent human teratogen, caused major birth defects in ~10,000 children •Phocomelia History of …
Thalidomide: The Tragedy of Birth Defects and the ...
www.gvsu.edumultiple myeloma. In rural areas of the world that lack extensive medical surveillance initiatives, thalidomide treatment of preg-nant women with leprosy has continued to cause malformations. Research on thalidomide mechanisms of action is leading to a better understanding of molecular targets. With an improved