Guideline on adjustment for baseline covariates in ...

the primary analysis, and to help the sponsor with the ongoin g development of the drug. • In case of missing values in baseline covariates the principles for dealing with missing values as outlined e.g. in the Guideline on missing data in confirmatory clinic al trials (EMA/CPMP/EWP/1776/99 Rev. 1) applies.

  Analysis, Adjustment, Covariates, Baseline, Confirmatory, On adjustment for baseline covariates in