Dissolution of Gelatin Capsules: Evidence and Confirmation ...

on the bioavailability and clinical efficacy of drugs in gelatin capsules. Cases were also reported in which the bioavailability of the drug from the stressed capsules did not significantly alter in vivo performance when compared to freshly prepared capsules (10, 20–23). A comparison of the in vitro dissolution rate of drug release from stressed

  Clinical, Efficacy, Clinical efficacy