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CHAPTER 18 MEDICINAL CHEMISTRY 18.1 Introduction
www.siue.edu18.2 Antibiotics 339 O O O CH 3 OH OCH 3 CH 3 O CH 3 O O N(CH 3)2 CH CH 3 3 CH 3 CH O 3 HO CH 3 erythromycin CH 3CH 2 1952 HO HO CH 3 Tyr Glu Asp Phe Orn Val Phe Pro D-Phe Leu Tyrocidine A 1939 D-The search for new antibiotics continues with an emphasis on discovery of