Search results with tag "Antisense"
CMC Regulatory Considerations for Oligonucleotide Drug ...
pqri.orgFeb 03, 2017 · Review Considerations for Synthetic Oligonucleotides: Current Practices • Confusion about whether USP Salt Policy applies to salt oligonucleotide drugs, partly because oligonucleotides (approx. molecular mass: 7000 to 8000) are not perceived as small molecules • Based on antisense oligonucleotide structure, design and mechanism
ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS
www.ema.europa.euadministered antisense oligonucleotides. If clinically indicated, urine protein testing (preferably using a first morning urine specimen) is recommended. For persistent elevated urinary protein, further evaluation should be considered.
Ruanjaikaen ASO Purification Platform BPI West …
download.knect365lifesciences.com2/24/2017 2 Biogen | Confidential and Proprietary 3 Introduction: Antisense oligonucleotides (ASOs) o What are they? o How are they made? o Current process vs. Biogen’s platform
Antisense Treatment for Myasthenia Gravis - BioLineRx
www.biolinerx.comAntisense Treatment for Myasthenia Gravis Experience with Monarsen JON D. SUSSMAN,a ZOHAR ARGOV,b DAVID MCKEE,a ELI HAZUM,c SOLLI BRAWER,c AND HERMONA SOREQb aDepartment of Neurology, Greater Manchester Neuroscience Centre, Hope Hospital, Salford, United Kingdom bDepartment of Neurology, Hadassah-Hebrew University Medical Centre, Hebrew University, …