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Search results with tag "Investigation of chiral active substances"
INVESTIGATION OF CHIRAL ACTIVE SUBSTANCES
www.ema.europa.eu383 _____ 3CC29a INVESTIGATION OF CHIRAL ACTIVE SUBSTANCES PREAMBLE This note for guidance considers active substances with one or more stereogenic centres
INVESTIGATION OF CHIRAL ACTIVE SUBSTANCES
www.ema.europa.euDiastereoisomers: Stereoisomers that are not enantiomeric of each other are termed diastereoisomers. Racemate: equimolar mixture of enantiomers. Stereogenic centre: an atom where the interchange of two ligands or substituents creates a new stereoisomer 2.2 Nomenclature Unambiguous nomenclature should be used throughout the dossier to describe …