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2.07 Protocol Name: CHOP & Rituximab

2 07 R- chop Version 2 0 Page 1 of 5 Protocol name : chop & Rituximab Indication Intermediate and high grade, B-cell non-Hodgkins lymphoma expressing CD20. Second or third line therapy for low grade, B cell non-Hodgkins lymphoma expressing CD20. Pre-treatment Evaluation Document histological sub-type of lymphoproliferative disorder according to WHO classification. Document disease stage clinically, including presence or absence of B symptoms. Investigations should include CT scan of chest, abdomen and pelvis, bone marrow aspirate & trephine biopsy. Document FBC (with film), U&E, creatinine, LFTs, calcium, glucose, immunoglobulin levels and a direct antiglobulin test. LDH is also required for patients with aggressive NHL.

2 07 R-CHOP Version 2 0 Jul08.doc Page 1 of 5 2.07 Protocol Name: CHOP & Rituximab Indication • Intermediate and high grade, B-cell non-Hodgkins

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