Transcription of 2 associated birth defects Craniofacial anomalies …
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2 associated birth defects Craniofacial anomalies …
15 Global registry and database on Craniofacial anomaliesCraniofacial anomalies andassociated birth distribution of Craniofacial anomaliesCongenital anomalies (CA) are a major cause of infant mortality andchildhood morbitity, affecting 2-3% of all babies. Approximately 1% ofthese newborns have syndromes or multiple anomalies ; CFA are often acomponent part. Syndromes are composed of multiple malformationsthought to be etiologically and/or pathogenetically related. Syndromes thathave cleft lip and/or cleft palate as one of the features are of interest inthe quest for etiologic and pathogenetic factors, and it is estimated that30% of cleft cases are syndromic. Conversely, therefore, approximately70% are suggest that associated anomalies occur with a frequency of 44 %to 64 % in patients with clefts (Cohen, 1978).
15 Global registry and database on craniofacial anomalies Craniofacial anomalies and 2 associated birth defects 2.1 Global distribution of craniofacial anomalies
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