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5. EPIDEMIOLOGICAL STUDIES

2775. EPIDEMIOLOGICAL STUDIESThis chapter reviews observational and experimental epidemio-logical STUDIES that have been conducted to determine associationsbetween disinfected drinking-water and adverse health outcomes. Dis-infection practices vary throughout the world. Applied and residualconcentrations have varied over the years and from country study designs, sources of systematic and randomerror (bias), and guidelines for assessing the causality of associationsare discussed in section EPIDEMIOLOGICAL STUDIES of exposures todisinfected drinking-water and to specific DBPs are evaluated in sec-tions and , EPIDEMIOLOGICAL STUDIES have been conducted todetermine possible associations between adverse health-related out-comes and drinking-water disinfected with chlorine and drinking-water was studied most often, and studiesprimarily compared health risks associated with chlorinated drinking-water from surface water sources with those a

Applied and residual concentrations have varied over the years and from country to country. ... comes and drinking-water disinfected with chlorine and chloramine. Chlorinated drinking-water was studied most often, and studies ... lead to a false or spurious association or a measure of risk that departs systematically from the true value. All ...

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