Transcription of Alcohol and Neurotransmitter Interactions
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Alcohol and Neurotransmitter Interactions
144 ALCOHOLHEALTH& RESEARCHWORLDS cientists have long sought themechanisms by which alcoholacts on the brain to modify be-havior. An important finding is thedemonstration that Alcohol can affectthe function of specific neurotransmit-ters1(Lovinger et al. 1989). Studies ofneurotransmitters and the receptors towhich they bind have provided dataon both the structure and the mecha-nism of action of these molecules aswell as clues to their role in , the function of individualneurotransmitters and their receptorscannot entirely explain a syndrome ascomplex as systems do notfunction in isolation. Therefore, scien-tists are paying increasing attention tothe integration of communicationsystems in the brain. Although thestudy of neural integration is in itsinfancy, enough has been learned tohelp guide future research.
1997). Alcohol’s actions on inhibitory neurotransmission in this lower area of the central nervous system may cause some of alcohol’s behavioral effects. Alcohol might also increase in-hibitory neurotransmission by increas-ing the activity of inhibitory neuro-modulators, such as adenosine. Activation of the adenosine system
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