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An Introduction to Clinical Trials: Type of Studies Design ...

An Introduction to Clinical Trials: Design IssuesEdgar R Miller III PhD, MDWelch Center for Prevention, Epidemiology and Clinical ResearchJohns Hopkins UniversitySchool of Medicine and Bloomberg School of Public Health2 Type of Studies Non-experimental (Observational) Case report Case series Cross-sectional (survey) Case-control Prospective, observational (cohort) Experimental Randomized, Clinical trial (RCT) 3 Study designs Observational Studies : Observeboth exposures and outcomes Experimental Studies ( Clinical trials) Assignexposures Observeoutcomes4 Advantages of Clinical Trials Often provides the strongest evidence in support of cause-effect relationships Basis for Clinical and public health policy Minimize/eliminate bias and confounding5 Randomized Clinical Tr

Jul 07, 2013 · An Introduction to Clinical Trials: Design Issues Edgar R Miller III PhD, MD Welch Center for Prevention, Epidemiology and Clinical Research Johns Hopkins University School of Medicine and Bloomberg School of Public Health 2 Type of Studies • Non-experimental (Observational) – Case report – Case series – Cross-sectional (survey ...

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