Transcription of Anemia: Pathophysiology & Diagnostic Classification
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Anemia: Pathophysiology & Diagnostic Classification
Anemia: Pathophysiology & Diagnostic ClassificationLinda M. S. Resar, Professor of Medicine,Oncology & PediatricsKey ConceptsA.) Define anemiaB.) Describe the metabolic and physiologic responses to anemia, with emphasis on those that give rise to the clinical findings C.) Introduce the systemic Classification of anemia on the basis of morphology and red blood cell productionImportant Concepts from the Lecture:A.) The metabolic and physiologic changes that occur in response to anemia1.) Changes in cardiac output and perfusion of different organs ( , brain, skin, kidney and muscle)2.) How increased RBC mass affects oxygen delivery3.) How decreased oxygen affinity affects the ability to deliver oxygen to tissuesImportant Concepts from the Lecture (Continued):A.) Metabolic and physiologic responses to anemia(cont.
Hemorrhage or blood loss Unstable hemoglobins Infections Chronic disease 4.) Normocytic, abnormal morphology: Hemoglobinopathies, (SS, SC, CC) Hereditary Spherocytosis Autoimmune hemolytic anemia Some enzymatic deficiencies. Q: A 52-year-old woman presents to you with complaints
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