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Anesthetic Concerns in Patients Presenting with …

Anesthetic Concernsin PatientsPresenting withRenal FailureGebhard Wagener,MDa, Tricia E. Brentjens,MDa,b,*RENAL PHYSIOLOGYThe foremost function of the kidneys is to maintain fluid and electrolyte balance, bya tightly controlled system that is able to maintain homeostasis even in perilous meta-bolic situations. Other tasks include the excretion of metabolic waste products,control of vascular tone, and regulation of hematopoesis and bone kidneys are the best-perfused organ per gram of tissue and receive 20% of thecardiac output. Global renal blood flow is autoregulated and is kept constant ata mean arterial pressure of 50 to 150 mm Hg in normotensive flowto the glomerulus is regulated through the afferent and efferent sphincters, whichadjust the glomerular filtration pressure.

Anesthetic Concerns in Patients Presenting with Renal Failure Gebhard Wagener, MDa, Tricia E. Brentjens, MDa ,b * RENAL PHYSIOLOGY The foremost function of the kidneys is to maintain fluid and electrolyte balance, by

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