Transcription of Anthracycline 類化療藥物引起的心臟毒性概論
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Anthracycline 類化療藥物引起的心臟毒性概論
101 98 10 1 Anthracycline Anthracyclines Anthracyclines DNA DNA Polymerases DNA RNA Anthracyclines Anthracyclines doxorubicin Fe-dependent Fe-independent doxorubicin (Oxidative stress) ROS(Reactive oxygen species) 1. [6] doxorubicin 400 550 700 mg/m2 3% 7% 18% [3] doxorubicin 550 600 600 mg/m2 4% 18% 36% doxorubicin 550 mg/m2 Epirubicin 900 mg/m2[4] Anthracyclines Anthracyclines Anthracyclines 2.
新光藥訊第101 期98 年10 月 3 出現心肌受損的比例也比傳統Doxorubicin 低，但仍須長期監測並繼續評估 此劑型之Doxorubicin 在降低心毒性上的成效。
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