Antibiotic Use for Sepsis in Neonates and Children: 2016 …

1 Antibiotic Use for Sepsis in Neonates and children : 2016 evidence Update Aline Fuchsa, Julia Bielickia,b, Shrey Mathurb, Mike Sharlandb, Johannes N. Van Den Ankera,c a Paediatric Pharmacology and Pharmacometrics, University children 's Hospital Basel, Basel, Switzerland b Paediatric Infectious Disease Research Group, Institute for Infection and Immunity, St George's University of London, London, United Kingdom c Division of Clinical Pharmacology, children s National Health System, Washington, DC, USA WHO-Reviews 2 TABLE OF CONTENTS 1. INTRODUCTION .. 3 Aims .. 3 Background .. 3 Definition and diagnosis .. 3 Neonatal Sepsis .. 3 Paediatric Sepsis .. 4 Community versus hospital acquired Sepsis .. 5 Microbiology .. 5 Burden of Sepsis .. 5 Current WHO guidelines .. 7 Trial design .. 8 2. METHODS.

in neonates and children must be evaluated. For this purpose, a number of reviews have been commissioned to address these aspects. This review collates evidence to support curr ent empiric antibiotic recommendation s for suspected or confirmed sepsis in neonates and children according to the most recent ( ≥ year 2012) relevant studies .

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  2016, Evidence, Children, Sepsis, Sepsis in neonates and children, Neonates, For sepsis in neonates and children, In neonates and children

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