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Antiphospholipid Syndrome (APS) Diagnostic Algorithm

Figure. Antiphospholipid Syndrome (APS) Diagnostic Algorithm1,11-13 Vascular Thrombosis and/or Pregnancy Morbidity Clinical Criteria laboratory Criteria Pregnancy morbidity defined as at least 1 of the following: 1) 1 unexplained deaths of morphologically normal fetus 10 weeks gestation 2) 1 premature births of morphologically normal fetus <34 weeks gestation, because of eclampsia, pre-eclampsia, or placental insufficiency 3) 3 consecutive spontaneous abortions before 10th week of gestation Cardiolipin antibody negative 2-GPI antibody negative APS identified Cardiolipin antibody positive 2-GPI antibody positive IgG and/or IgM >40 GPL/MPL on 2 tests, 12 wks apart IgG and/or IgM >99th percentile of controls on 2 tests, 12 wks apart IgG and/or IgM 40 GPL/MPL on 2 tests, 12 wks apart IgG and/or IgM 99th percentile of controls on 2 tests, 12 wks apart Abnormal LA positive LA

Figure. Antiphospholipid Syndrome (APS) Diagnostic Algorithm1,11-13 . Vascular Thrombosis and/or Pregnancy Morbidity . Clinical Criteria . Laboratory Criteria

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  Laboratory, Syndrome, Diagnostics, Antiphospholipid syndrome, Antiphospholipid

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