Appendix F: Guidelines for Standard Method Performance ...

2016 AOAC INTERNATIONALC ontentsIntroduction to Standard Method Performance Requirements 1 Annex A: Format of a Standard Method Performance Requirement 5 Annex B: Classification of methods 11 Annex C: Understanding the POD Model 12 Annex D: Definitions and Calculations of HorRat Values from Intralaboratory Data 13 Annex E: AOAC Method Accuracy Review 15 Annex F: Development and Use of In-House reference Materials 16 Introduction to Standard Method Performance RequirementsStandard Method Performance Requirements (SMPRs ) are a unique and novel concept for the analytical methods community. SMPRs are voluntary consensus standards , developed by stakeholders, that prescribe the minimum analytical Performance requirements for classes of analytical methods . In the past, analytical methods were evaluated and the results compared to a gold Standard Method , or if a gold Standard Method did not exist, then reviewers would decide retrospectively if the analytical Performance was acceptable.

model, HorRat values, reference materials, and method accuracy and review. As with the informative tables, these annexes are intended to provide guidance and information to the working groups. Initiation of an SMPR See Figure 1 for a schematic flowchart diagram of the SMPR

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