Transcription of Argatroban for anticoagulation in continuous renal ...
{{id}} {{{paragraph}}}
Example: bankruptcy
Argatroban for anticoagulation in continuous renal ...
Argatroban for anticoagulation in continuous renalreplacement therapy*Andreas Link, MD; Matthias Girndt, MD; Simina Selejan, MD; Alexander Mathes, MD; Michael Bo hm, MD;Hauke Rensing, MDContinuous renal replacementtherapy (CRRT) is proven ef-fective for critically ill pa-tientswith (acute) renal fail-ure (1, 2). In patients with heparin-induced thrombocytopenia type II(HIT-II) requiring CRRT effective anti-coagulation, it is necessary to avoidthrombembolic complications (3, 4).The options for anticoagulant treat-ment in critically ill patients withHIT-II requiring CRRT are limited andinclude danaparoid and direct danaparoid hasbeen used in HIT-II for a long time sev-eral major drawbacks have been with heparin/platelet fac-tor 4 antibodies in 15% of cases (5), pro-longation of half-life in renal failure up to36 48 hours (6), and an increased riskfor bleeding events in 46% (7) have beendescribed.
Argatroban for anticoagulation in continuous renal replacement therapy* Andreas Link, MD; Matthias Girndt, MD; Simina Selejan, MD; Alexander Mathes, MD; …
Tags:
Information
Domain:
Source:
Link to this page:
Please notify us if you found a problem with this document: