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Basics of LC/MS (5968-2543E)

Basics of LC/MSA PrimerContentsIntroduction ..2 Instrumentation ..4 Interfacing LC and MS ..4 Atmospheric Pressure ionization ..4 API- electrospray ..5 Atmospheric Pressure Chemical ionization (APCI) ..6 Scan and SIM ..7 Collision-Induced Dissociation ..8 Adapting LC Methods ..9 Applications ..10 Molecular Weight Determination .. 10 Combinatorial Chemistry .. 12 Pharmaceutical Applications .. 13 Biochemical Applications .. 14 Clinical Applications .. 16 Food Applications .. 16 Environmental Applications .. 182 Sample TypesLC/MS systems facilitate the analysis of samples that traditionally have beendifficult to analyze. Despite the power andusefulness of gas chromatography /massspectrometry (GC/MS), many compoundsare impossible to analyze with GC/MS.

Liquid Chromatography/Mass Spectrometry (LC/MS) is fast becoming the preferred ... API-electrospray ionization. 6 Atmospheric Pressure Chemical Ionization ... quadrupoles or ion traps. Electrospray is a soft ionization technique that produces a large number of molecular

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  Mass, Chromatography, Spectrometry, Ionization, Mass spectrometry, Electrospray, Electrospray ionization, Lc ms, Of lc ms

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