Transcription of BD FastImmune™ CD107a (H4A3)
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Becton, Dickinson and CompanyBD Biosciences2350 Qume DriveSan Jose, CA 95131 Research Use Only. Not for use in diagnostic or therapeutic procedures. Monoclonal Antibodies Detecting Human AntigensBD FastImmune CD107a (H4A3)FormCatalog numberAPC641581 Product availability varies by region. Contact BD Biosciences Customer Support or your local sales representative for APPLICATIONSThe BD FastImmune CD107a APC reagent is designed for the detection of degranulating T lymphocytes in activated whole blood and is intended for research use only. Applications include studies of cytotoxic CD8+ T- cell responses to viral and tumor antigens,1-6 correlation of T-cell cytolytic potential and cytokine expression,1 and live-cell sorting of functional antigen-specific CD8+ T The CD107a detection assay can also be used as an alternative to 51Cr release ,2,4 DESCRIPTIONS pecificityEach vial supplies sufficient reagents for 50 stimulated samples and 50 unstimulated control samples.
Page 3 23-8946-02 BD FACS™ 7-color setup beads (Catalog No. 335775) See the BD FACS 7-color beads product insert for instructions. PROCEDURE Because the staining for CD107a is carried out during cell activation in this assay,
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