Bilirubin (DIRECT) - Spectrum Diagnostics

Bilirubin ( direct )ColorimetricREF: 224 001 120 TestR1 direct Bilirubin 2 x 90 mlR2 Nitrite 1 x 7 mlIntended UseSpectrum Diagnostics Bilirubin reagent is intended for the in-vitroquantitative, diagnostic determination of Bilirubin in human serum on both automated and manual average level of the Bilirubin produced in humans from differentsources ranges between 250 to 300 mg/day, of which 85% is derivedfrom the heme moiety of the haemoglobin released from senescenterythrocytes that are destroyed in the reticuloendothelial remaining 15 % is produced from erythrocytes destroyed in thebone marrow and from catabolism of other heme containing proteinssuch as cytochromes and it is produced in the peripheral tissues, Bilirubin is transportedto the liver in association with albumin. In the liver, Bilirubin isconjugated with glucuronic acid for solubilization and subsequenttransport through the bile duct and elimination via the digestive or conditions which, through hemolytic processes, produce Bilirubin faster than the liver can metabolize it, cause thelevels of unconjugated (indirect) Bilirubin to increase in the duct obstruction or damage to hepatocellular structure causesincreases in the levels of both conjugated ( direct ) and unconjugated(indirect) Bilirubin in the PrincipleBilirubin is converted to colored diazotized sulfa

Bilirubin (DIRECT) Colorimetric REF: 224 001 120 Test R1 Direct Bilirubin 2 x 90 ml R2 Nitrite 1 x 7 ml Intended Use

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  Direct, Bilirubin, Colorimetric

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