Transcription of 「抑肝散は認知症のBPSDを改善するか」
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「抑肝散は認知症のBPSDを改善するか」
JHOSPITALIST network BPSD Randomized double-blind placebo-controlled mul3center trial of Yokukansan for neuropsychiatric symptoms in Alzheimer's disease. PMID 23359469 2016 4 3 PGY5 83 ( 5mg/day) MMSE 25/30 2P2X( ) 5mg/day first choice BPSD(Behavioral and Psycological Symptoms of Dementia) EBM 5 steps Step1 PICO Step2 Step3 Step4 Step5 Step1-4 Step1 PICO P: I : C: O: BPSD Step2 (primary studies) PubMed Yokukansan and dementia and BPSD Alzheimer s disease 2011 7 2013 1 22 ( ) P: Alzheimer s disease I : C O BPSD ( NPI-Q ) BPSD BPSD(Behavioral and Psycological Symptoms of Dementia) ( )
Introduction Alzheimer’s disease (AD), an age-associated brain dis-order, is among the most common diseases causing dementia. Its first symptom is memory loss, which becomes more serious as the disease progresses in most patients with AD. Mental and behavioral disturbances in the form of behavioral and psychological symptoms
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