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Breast Cancer Study Case

1 Breast Cancer Study CASE Scenario A Carol Edwards, a 39 year-old premenopausal woman, had a screening mammogram which revealed an abnormality in the right Breast . She had no palpable masses on Breast exam. A mammographically localized surgical biopsy was done and revealed a small ( cm) grade III infiltrating ductal carcinoma with some associated ductal carcinoma-in-situ (DCIS). The surgical margins were not clear ( Cancer cells were found at the posterior margin). Estrogen and progesterone receptors are negative. The patient has been given the diagnosis in a telephone conversation with the surgeon a few days after the biopsy, and they are now meeting to discuss definitive treatment.

breast. The latter is known as breast conservation therapy (BCT) and it is imperative that margins be clear and cosmetic results acceptable to the patient to qualify for this option. In addition to this, there must be unifocal disease only, not multicentric cancers. If there are multiple foci of carcinoma, the patient should have a mastectomy.

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