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Breast Cancer Study Case

1 Breast Cancer Study CASE Scenario A Carol Edwards, a 39 year-old premenopausal woman, had a screening mammogram which revealed an abnormality in the right Breast . She had no palpable masses on Breast exam. A mammographically localized surgical biopsy was done and revealed a small ( cm) grade III infiltrating ductal carcinoma with some associated ductal carcinoma-in-situ (DCIS). The surgical margins were not clear ( Cancer cells were found at the posterior margin). Estrogen and progesterone receptors are negative. The patient has been given the diagnosis in a telephone conversation with the surgeon a few days after the biopsy, and they are now meeting to discuss definitive treatment. Surgical treatment must address two issues: local control and staging. LOCAL CONTROL can be achieved by mastectomy or by wide re-excision (known as lumpectomy or partial mastectomy) followed by radiation to the Breast .

skin of the axilla and posterior upper arm. These may be divided or otherwise injured during the node dissection, resulting in temporary or permanent numbness. However, the most feared and significant complication associated with ALND is the development of lymphedema of the upper extremity. This condition occurs in

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