Transcription of BRIEF REPORTS …
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BRIEF REPORTS …
BRIEFREPORTSThe Antidepressant Properties of the Ketogenic DietPatricia Murphy, Sergei Likhodii, Kirk Nylen, and BurnhamBackground:The ketogenic diet is used to treat epilepsy refractory to anticonvulsant medication. Individuals with epilepsy often havebehavioral problems and deficits in attention and cognitive functioning. The ketogenic diet has been found to effect improvements inthese domains. It has also been suggested that the ketogenic diet may act as a mood :The present research used the Porsolt test, an animal model of depression, to determine whether the ketogenic diet hasantidepressant properties. Porsolt test scores of rats on the ketogenic diet were compared with those of rats on a control :The rats on the ketogenic diet spent less time immobile, suggesting that rats on the ketogenic diet, like rats treated withantidepressants, are less likely to exhibit behavioral despair.
This research was supported by funds from the Michael Bahen Chair of Epilepsy Research and Natural Sciences and Engineer-ing Research Council of Canada Grant #CHRP238016-00.
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