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Calibration Factor/Response Factor

Response/ Calibration FactorDefinitionsCalibration Factor :A measure of the chromatographic response of a target analyte relative to the mass Factor :A measure of the relative mass spectral response of an analyte compared to its internal : EPA R3 Quality Manual Rev 3 (1/12/04)DefinitionsCalibration Factor :A measure of the chromatographic response of a target analyte relative to the mass Factor :A measure of the relative mass spectral response of an analyte compared to its internal : EPA R3 Quality Manual Rev 3 (1/12/04) Calibration or response Factor representsthe slope of the line between the response for a given standard and the average Calibration Factor or response Factor of the standards for each analyte is then used to calculat

S = the sum of all the individual values In the equations above RF can be replaced with CF. Response/Calibration Factor. Equations for Concentration. External Standard Equation. C. x = A. x /CF. AVE. or. Internal Standard Equation. C. x = ((A. x)*(C. is)) / ((A. is)*(RF. AVE)) Benefits 1. Assumes linearity through the origin,

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