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CANNABIDIOL (CBD) Pre-Review Report - who.int

CANNABIDIOL (CBD) Pre-Review Report Agenda Item Expert Committee on Drug Dependence Thirty-ninth Meeting Geneva, 6-10 November 2017 39th ECDD (2017) Agenda item CANNABIDIOL (CBD) Page 2 of 27 Contents Acknowledgements .. 4 Summary .. 5 1. Substance identification .. 6 A. International Nonproprietary Name (INN) .. 6 B. Chemical Abstract Service (CAS) Registry Number .. 6 C. Other Chemical Names .. 6 D. Trade Names .. 6 E. Street Names .. 6 F. Physical Appearance .. 6 G. WHO Review History .. 6 2. Chemistry .. 6 A. Chemical Name .. 6 B. Chemical Structure .. 7 C. Stereoisomers .. 7 D. Methods and Ease of Illicit Manufacturing .. 7 E. Chemical Properties .. 9 F. Identification and Analysis .. 9 3. Ease of Convertibility Into Controlled Substances .. 10 4. General Pharmacology .. 11 A. Routes of administration and dosage .. 11 B. Pharmacokinetics .. 11 C. Pharmacodynamics .. 12 5. Toxicology.

39th ECDD (2017) Agenda item 5.2 Cannabidiol (CBD) Page 5 of 27 Summary Cannabidiol (CBD) is one of the naturally occurring cannabinoids found in cannabis plants. It is a 21-carbon terpenophenolic compound which is formed following decarboxylation from a

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