Transcription of Chapter 2 Vasopressors and Inotropes
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Chapter 2 Vasopressors and Inotropes
Kane-Gill and J. Dasta (eds.), High-Risk IV Medications in Special Patient Populations,DOI: , Springer-Verlag London Limited 2011 IntroductionMedication errors and adverse drug events occur more frequently in the intensive care unit compared to general care Adverse drug events become more likely as patients receive more medications. Sentinel events and medication errors are more common as the number of failing organs ,3 Vasopressors are fre-quently associated with adverse drug events and they are considered high-alert drugs by the Institute of Safe Medication Practices due to their increased potential to cause Vasopressors and Inotropes are used in patients with the highest acuity and under stressful situations which adds to the potential for errors. In addi-tion, dosing guidelines, ranges and units are not always standardized across agents at specific institutions or for a certain agent across institutions.
2 Vasopressors and Inotropes 73 Kidney Injury: Only a small amount of DA is excreted unchanged in the urine. Dopamine has been used at low doses in cases of acute or chronic renal insuffi-ciency in attempts to increase urine production or prevent worsening renal function.
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