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Chapter 4 Pedigree Analysis in Human Genetics

Chapter 4 Human Heredity by Michael Cummings 2006 Brooks/Cole-Thomson LearningChapter 4 Pedigree Analysis in Human Genetics Chapter 4 Human Heredity by Michael Cummings 2006 Brooks/Cole-Thomson LearningMendelian Inheritance in HumansPigmentation Gene and AlbinismFig. Chapter 4 Human Heredity by Michael Cummings 2006 Brooks/Cole-Thomson LearningTwoGenesFig. Chapter 4 Human Heredity by Michael Cummings 2006 Brooks/Cole-Thomson LearningThe Inheritance of Human TraitsDifficulties Long generation time Data must be obtained fromoffspring produced Experimental matings are notpossible Limited sample size Chapter 4 Human Heredity by Michael Cummings 2006 Brooks/Cole-Thomson LearningPedigree Analysis Pedigree is an orderly presentationof family information First step in studying the inheritanceof traits Important in predicting genetic risk May be incomplete due to difficultiescollecting information Chapter 4 Human Heredity by Michael Cummings 2006 Brooks/Cole-Thomson LearningPedigree Analysis Construct Pedigree using availableinformation Rule out all patterns of inheritancethat are inconsistent with the data May not have enough information toidentify the mode of

Chapter 4 Human Heredity by Michael Cummings ©2006 Brooks/Cole-Thomson Learning Chapter 4 Pedigree Analysis in Human Genetics

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