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Chapter 5: Major Metabolic Pathways

1 Michigan Technological UniversityDavid R. Shonnard1 Chapter 5: Major Metabolic PathwaysDavid ShonnardDepartment of Chemical EngineeringMichigan Technological UniversityMichigan Technological UniversityDavid R. Shonnard2 Presentation Outline:lIntroduction to MetabolismlGlucose MetabolismGlycolysis, Kreb s Cycle, RespirationlBiosysthesislFermentation2 Michigan Technological UniversityDavid R. Shonnard3 Metabolismis the collection of enzyme-catalyzed reactions that convert substrates that are external to the cell into various internal Technological UniversityDavid R. Shonnard4 Genetic Engineeringallows for the alteration of metabolism by insertion or deletion of selected genes in a predetermined manner ( Metabolic Engineering). An understanding of Metabolic Pathways in the organism of interest is of primary importance in bioprocess development. Introduction: Metabolism, Genetic Engineering and Bioprocessing3 Michigan Technological UniversityDavid R.

“Metabolic Engineering: Principles and Methodologies” Stephanopoulos, Aristidou, and Nielsen, Academic Press, 1998 1. Rates of intra-cellular reactions can be measured by extra-cellular product accumulation. (ATP) 2. The redox balance (balance on NADH consumption and generation) must balance. David R. Shonnard Michigan Technological ...

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pages.mtu.edu

balance equations we choose the boundaries and then note the quantities of mass, energy, or momentum that cross the boundaries (Figure 2). A closed system is a system that does not have any mass crossing its boundaries.

  Balance, Energy

CM3215 Fundamentals of Chemical Engineering …

pages.mtu.edu

Control Valve Lecture, CM3215 Morrison 2/17/2016 1 CM3215 Fundamentals of Chemical Engineering Laboratory Professor Faith Morrison Department of Chemical Engineering

  Laboratory, Chemical, Engineering, Fundamentals, Of chemical engineering, Cm3215 fundamentals of chemical engineering, Cm3215, Cm3215 fundamentals of chemical engineering laboratory

Basic Concepts of Human Genetics - pages.mtu.edu

pages.mtu.edu

1 Basic Concepts of Human Genetics • The genetic information of an individual is contained in 23 pairs of chromosomes. Every human cell contains the 23 pair of chromosomes. • One pair is called sex chromosomes Male: XY Female: XX • Other 22 pairs of homologous chromosomes are called autosomes. • The autosome …

  Genetic

Pumping System Curves - Michigan Technological …

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Pumping System Head CM3215 FAM 3Mar2014 1 CM3215 Fundamentals of Chemical Engineering Laboratory Professor Faith Morrison Department of Chemical Engineering

  System, Fundamentals, Pumping, Curves, Pumping system curves

Chapter 4 - Student

pages.mtu.edu

In Chapter 4, the following problem modules explain the heat transfer processes involved in fuel cell vehicles and in the processes for producing fuel for fuel cells. 4.1-1 Heat Loss through a Stainless Steel Bipolar Plate

  Chapter, Students, Heat, Chapter 4

Heat Exchanger Effectiveness

pages.mtu.edu

Heat Exchanger Effectiveness ... Double-pipe or 1-1 Shell-and-Tube Heat Exchangers ©Faith A. Morrison, Michigan Tech U. 8 Final Exam CM 310 November 16, 1998 ... The heat capacity of the oil is 1.89 kJ/kg K, and the average heat capacity of water over the temperature range of interest is 4.192 kJ/kg K. The overall heat-transfer coefficient of ...

  Tubes, Heat, Exchanger, Effectiveness, Shell, Shell and tube heat, Heat exchanger effectiveness

Introduction to Electromagnetic Theory

pages.mtu.edu

1/19/18 1 Lecture topics • Laws of magnetism and electricity • Meaning of Maxwell’s equations • Solution of Maxwell’s equations Introduction to Electromagnetic Theory

  Introduction, Theory, Electromagnetic, Introduction to electromagnetic theory

Compressibility Factor from Redlick-Kwong Equations

pages.mtu.edu

Compressibility Factor from Redlick-Kwong Equations (Dr. Tom Co 9/2/08) Working Equations: (based on Cutlip and Shacham, 2008, pp. 101-103) Let be pressure in …

  Form, Factors, Compressibility, Kwong, Compressibility factor from redlick kwong, Redlick

STEAM TABLES - Michigan Technological University

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Saturated Steam: TEMPERATURE Table STEAM TABLES ( from M. D. Koretsky, "Engineering and Chemical Thermodynamics", John Wiley & Sons, 2004)

  Engineering, Table, Steam, Steam tables

ROBOT OPERATIONS - Michigan Technological University

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R-J3, R-J3iB and R-30iA Controller This training focuses on the FANUC Robotics R-J3, R-J3iB and R-30iA controller. The R-J3 series uses advanced technology packaged in a

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TABLE OF CONTENTS - Metabolic Renewal

www.metabolicrenewal.com

SHMEC is a set of crucial biofeedback signals that allow you to measure your hormonal and metabolic balance. But instead of an expensive lab test that gives you results that are confusing; measuring your SHMEC helps you pinpoint precisely how your metabolism is operating and where the problem areas may be.

  Balance, Content, Table of contents, Table, Metabolic, Metabolic balance

Acid Base Balance

www.uhbristol.nhs.uk

metabolic disorders e.g. DKA through regulation of pCO 2 Sepsis through regulation of pCO 2 But if the changes in pH are related to a respiratory disorder e.g. consolidation / pneumothorax, then the respiratory system will be limited in it’s ability to adjust the pCO 2 and affect the pH Renal System Controls acid base balance through several ...

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Fluid, Electrolyte, and Acid-Base Balance

mymission.lamission.edu

Fluid balance refers to the proper levels of water and ... Metabolic Acidosis: increased production of acids such as lactic acid, fatty acids, and ketone bodies, or loss of blood bicarbonate (such as by diarrhea), resulting in a fall in blood pH to below normal.

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ABG Quick Interpretation

www.uoflhealthnetwork.org

Metabolic Component Facts: Body will not overcompensate when it comes to acid/base balance so: pH midpoint is 7.4 If pH on report is < 7.4 = original problem was acidosis in nature If pH on report is > 7.4 = original problem was alkalosis in nature Examples: 1. pCO2 is High and pH is 7.37 = compensated Respiratory Acidosis because in spite of

  Balance, Interpretation, Quick, Metabolic, Abg quick interpretation

The Endocrine System

pubs.niaaa.nih.gov

Metabolic effects ACTH + + + Figure 1 The hypothalamic-pituitary-adrenal axis. In response to almost any type of stress, either physical or psychological, the hypothalamus secretes corticotropin-releasing factor (CRF), which in turn increases secretion of adrenocortotropic hormone (ACTH) by the anterior pituitary gland. In

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METABOLIC PATHWAYS

www.jiwaji.edu

regulation & in the subsequent metabolic fate of the pyruvate formed. •In aerobic organisms, glycolysis is the prelude to Citric acid cycle and ETC. •Glycolysis is the central pathway for Glucose catabolism.

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