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Chapter 5: Major Metabolic Pathways

1 Michigan Technological UniversityDavid R. Shonnard1 Chapter 5: Major Metabolic PathwaysDavid ShonnardDepartment of Chemical EngineeringMichigan Technological UniversityMichigan Technological UniversityDavid R. Shonnard2 Presentation Outline:lIntroduction to MetabolismlGlucose MetabolismGlycolysis, Kreb s Cycle, RespirationlBiosysthesislFermentation2 Michigan Technological UniversityDavid R. Shonnard3 Metabolismis the collection of enzyme-catalyzed reactions that convert substrates that are external to the cell into various internal Technological UniversityDavid R. Shonnard4 Genetic Engineeringallows for the alteration of metabolism by insertion or deletion of selected genes in a predetermined manner ( Metabolic Engineering). An understanding of Metabolic Pathways in the organism of interest is of primary importance in bioprocess development.

Catabolism Metabolic reactions in the cell that degrade a substrate into smaller / simpler products. Glucose → CO 2 Anabolism Metabolic reactions that result in the synthesis of larger / more complex molecules. 4 ... Principles of ME and Mixed Acid Fermentation

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