Transcription of Chapter 7: Measles
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VPD surveillance ManualMeasles: Chapter 7: MeaslesPaul A. Gastanaduy, MD, MPH; Susan B. Redd; Nakia S. Clemmons, MPH; Adria D. Lee, MSPH; Carole J. Hickman, PhD; Paul A. Rota, PhD; Manisha Patel, MD, MS I. Disease DescriptionMeasles is an acute viral illness caused by a virus in the family paramyxovirus, genus Morbillivirus. Measles is characterized by a prodrome of fever (as high as 105 F) and malaise, cough, coryza, and conjunctivitis, followed by a maculopapular The rash spreads from head to trunk to lower extremities. Measles is usually a mild or moderately severe illness. However, Measles can result in complications such as pneumonia, encephalitis, and death. Approximately one case of encephalitis2 and two to three deaths may occur for every 1,000 reported Measles rare long-term sequelae of Measles virus infection is subacute sclerosing panencephalitis (SSPE), a fatal disease of the central nervous system that generally develops 7 10 years after infection.
VPD Surveillance Manual 7 Measles: Chapter 7.2 Post-elimination era During 2001–2008, 557 measles cases were reported in the United States.14, 15 The median number of measles cases reported per year was 56 (range: 37–140 cases/year).
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