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Colonization Versus Infection - API

Colonization Versus Infection CHAPTER. R. Soman 42. Introduction wounds like osteomyelitis with/without a draining There are many clinical situations when Infection sinus and diabetic foot ulcers, cultures from post- is suspected but tests do not reveal the causative operative drains, positive urine cultures in an organism. On the other hand sometimes an organism asymptomatic patient and in a catheterized patient, is isolated but it is difficult to decide whether it is a sputum/respiratory specimen showing organisms in contaminant, colonizer or a true pathogen. a patient with suspected pneumonia, blood cultures in a patient with indwelling central venous catheter, We live in a sea of microbes and so it is not arterial line, hemodialysis catheter.

Colonization Versus Infection 331 the other hand, an organism isolated from a non sterile specimen like sputum or a wound swab may be a colonizer. However it may be a true invader

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