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COVID-19 vaccine safety update

National Center for Immunization & Respiratory DiseasesCOVID-19 vaccine safety updateAdvisory Committee on Immunization Practices (ACIP)January 27, 2021 Tom Shimabukuro, MD, MPH, MBACDC COVID-19 vaccine Task Force vaccine safety TeamDisclaimer The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention (CDC) or the Food and Drug Administration (FDA) Mention of a product or company name is for identification purposes only and does not constitute endorsement by the CDC or FDAT opics V-safe update vaccine adverse Event Reporting System (VAERS) surveillance update Clinical Immunization safety Assessment (CISA) Project update vaccine safety Datalink (VSD) surveillance update update on anaphylaxis following COVID-19 vaccination Reports of deaths and mortality following COVID-19 vaccination3 This Photoby Unknown Author is licensed under CC BY-SACall centerThis Photo by Unknown Author is licensed under CC BY-SAVaccine r

Vaccine Adverse Event Reporting System (VAERS) Strengths. National data Rapidly detects safety signals Can detect rare adverse events Data available to public. Limitations. Reporting bias Inconsistent data quality and completeness of information Lack of unvaccinated comparison group Not designed to assess causality ‒ ‒

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  Causality, Adverse

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