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Deconstructing the Complete Blood Count (CBC)

The Children's Mercy Hospital, 2017 Lauren Amos, MDPediatric Coagulation Medicine Fellow24thAnnual Advanced Practice Nursing ConferenceSeptember 7th, 2018 Deconstructing the Complete Blood Count (CBC)Outline Introduction Defining components of the CBC with differential Interpreting the CBC with differential Cases ReferencesBloodHansen JT. Netter s Clinical AnatomyWhy check? Monitor overall health Screen for some diseases Confirm or make a diagnosis based on a patient s symptoms Monitor an existing condition Monitor body s response to medical treatment Most informative singletest Relatively inexpensiveWhat s normal? Normal ranges from lab to lab (reference ranges should be included) Normal depends on age, sex, pregnancy status, altitude The Children's Mercy Hospital, 2017 Defining the Components of CBCW hite Blood cells (WBC) Also known as leukocytes Protect body against infection and fight foreign material Use WBC to: help identify if an infection is present differentiate between different types of infection See how body is respondi

Thrombocytosis in Children Relatively common in young children Usually transient, benign finding secondary to infection/inflammation – Repeat in 1-2 months and will likely resolve Platelets are acute phase reactants Reactive thrombocytosis – Iron deficiency – Major trauma – Surgery – Postsplenectomy 40

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