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Development and reliability of a structured interview ...

Observer-rated depression rating scales are used in clinical trials ofantidepressants to select patients for study, and to assess theefficacy of the treatment being tested. The importance of thequality of ratings in clinical trials has recently been evidence suggests that the quality of ratings canmake the difference between a failed trial and one in which drugseparates from , any method that improves thequality of clinical trial ratings may improve our ability to conductsuccessful antidepressant trials. We describe the Development ofa structured interview guide for the Montgomery A sbergDepression Rating scale (MADRS) and its test retest reliability ,assessed in a sample of 51 persons with varying levels of A sberg depression Rating ScaleThe MADRS was developed in the late 1970s from items that werefound in several studies to be sensitive to change with anti-depressant its publication the scale has becomeincreasingly popular worldwide.

many rating scales, including the Hamilton scales for depression (SIGH–D) 14 and anxiety (SIGH–A). 17,18 In general, they are designed to approximate an expert administration of the scale.

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  Development, Scale, Reliability, Ratings, Hamilton, Depression, Structured, Development and reliability of a structured

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