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Diagnosing, Staging, and Treating Chronic Kidney Disease ...

Chronic Kidney Disease (CKD) is diagnosed based on evaluation of all available clinical and diagnostic information in a stable patient. Following diagnosis of CKD, the IRIS Board recommends using serum creatinine or SDMA (ideally both) to stage CKD with substaging based on assessment of arterial blood pressure and , Staging, and Treating Chronic Kidney Disease in Dogs and CatsJun 13 Jun 12 Jun 11 CreatinineCreatinine increasing within the reference interval where no prerenal cause is apparentreference intervalJulyAugSeptJuneSDMASDMA increasing within the reference interval where no prerenal cause is apparentreference intervalOne or more of these diagnostic findings:To diagnose Stage 1 and early Stage 2 CKDP ersistent increased SDMA* >14 g/dLBoth of these diagnostic findings:1234 Persistent renal proteinuria UPC > in dogs; UPC > in catsUrine protein to creatinine (UPC) ratio Sept 15 Oct 15 Nov creatinine and SDMA concentrationsResults of both tests should be interpreted in light of patient s hydration specific gravity< specific gravity< Feline Canine Kidney imagingTo diagnose more advanced CKD (late Stage 2 4)OR12 Clinical signs and physical examination findings worsen with increasing severity of Kidney Disease Step 1: Diagnose CKDC linical presentationConsider age, sex

Clinical signs and physical examination findings worsen with increasing severity of kidney disease Step 1: Diagnose CKD Clinical presentation Consider age, sex, breed predispositions, and relevant historical information, including medication history, toxin/toxicant exposure, and diet. Can be subclinical in early stage CKD. Signs may include

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