Transcription of Dilution and Concentration - Lippincott Williams & Wilkins
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Dilution and Concentration - Lippincott Williams & Wilkins
Chapter 10207 Dilution and ConcentrationOBJECTIVESUpon completion of this chapter, the technician student willbe able to: Describe the relationship of active ingredients and diluents if the amount of active ingredient remains constant and the amount of diluent is increased ordecreased. Determine the percent strength and ratio strength of a given product when the active ingredient remains constant and the amount of diluent is increased ordecreased. Determine the volume of solution of a desired strengthgiven a specified quantity of any given strength. Determine the volume of a specified stock solutionneeded to prepare a given solution. Determine the quantity of an active ingredient in a specified amount of solution needed to prepare a given solution. Define the alligation methods of problem solving. Use the alligation methods (alligation alternate and alligation medial) to determine the percent strength of alcohol mixtures. Use the alligation methods (alligation alternate and alligation medial) to determine relative amounts of components mixed together to make a mixture of arequired Alligation Alligation alternate Alligationmedial Diluent Stock solution456X789 % 11/20/06 2:45 PM Page 207 Chapter 9 addresses problems arising from the quantitative relationship betweenspecific ingredients and the pharmaceutical preparation as a whole.
4 5 6 X 1 2 3 – 0 † = + 789— % C.. Rules to Simplify the Calculation These two rules, wherever they may be applied, greatly simplify the calculation: 1. When ratio strengths are given, convert them to percentage strengths before setting up a proportion. It is much easier to solve using a decimal or percent, like
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