Transcription of Dosage Form Design: Pharmaceutical and Formulation ...
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Dosage Form Design: Pharmaceutical and Formulation ...
CHAPTER prescribe. The general area of study concerned with the Formulation , manufacture, stability, and effectiveness of Pharmaceutical Dosage forms is termed proper design and Formulation of a Dosage form requires consideration of the physi-cal, chemical, and biologic characteristics of all of the drug substances and Pharmaceutical ingredients to be used in fabricating the prod-uct. The drug and Pharmaceutical materials must be compatible with one another to produce a drug product that is stable, effi cacious, attrac-tive, easy to administer, and safe. The product should be manufactured with appropriate mea-sures of quality control and packaged in contain-ers that keep the product stable. The product should be labeled to promote correct use and be Drug substances are seldom administered alone; rather they are given as part of a Formulation in combination with one or more nonmedicinal agents that serve varied and specialized pharma-ceutical functions.
CHAPTER 4 • PHARMACEUTICAL AND FORMULATION CONSIDERATIONS 93 liquids or may be extemporaneously prepared into an oral liquid by the pharmacist. However, certain tablets and capsules that are designed for controlled release should not be crushed or chewed, because that would interfere with their integrity and intended performance.
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