DOSAGE FORMS AND STRENGTHS ——— RYBELSUS ...

1 See the Full Prescribing Information for instructions on switching between OZEMPIC and RYBELSUS ( ). DOSAGE FORMS AND STRENGTHS Tablets: 3 mg, 7 mg and 14 mg (3). CONTRAINDICATIONS Personal or family history of medullary thyroid carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type 2 (4). Prior serious hypersensitivity reaction to semaglutide or any of the excipients in RYBELSUS (4). WARNINGS AND PRECAUTIONS Pancreatitis: Has been reported in clinical trials. Discontinue promptly if pancreatitis is suspected. Do not restart if pancreatitis is confirmed ( ). Diabetic Retinopathy Complications: Has been reported in a cardiovascular outcomes trial with semaglutide injection.

2 DOSAGE AND ADMINISTRATION 2.1 Important Administration Instructions • Instruct patients to take RYBELSUS® at least 30 minutes before the first food, beverage, or other oral medications of the day with no more than 4 ounces of plain water only [see Clinical Pharmacology (12.3)]. Waiting less than 30 minutes, or taking RYBELSUS® with

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