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DRUG NAME: Etoposide

Etoposide DRUG NAME: Etoposide SYNONYM(S): VP-161 COMMON TRADE NAME: VEPESID 2, etopophos ( Etoposide phosphate)3,4 CLASSIFICATION: topoisomerase II inhibitor1 Special pediatric considerations are noted when applicable, otherwise adult provisions apply. MECHANISM OF ACTION: Etoposide is a semisynthetic derivative of the podophyllotoxins, an epipodophyllotoxin. It inhibits DNA topoisomerase II, thereby inhibiting DNA synthesis. Etoposide is cell cycle dependent and phase specific, affecting mainly the S and G2 phases1.

Etoposide DRUG NAME: Etoposide SYNONYM(S): VP-161 COMMON TRADE NAME: VEPESID®2, ETOPOPHOS® (etoposide phosphate)3,4 CLASSIFICATION: topoisomerase II inhibitor

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Transcription of DRUG NAME: Etoposide