Transcription of EASL Clinical Practice Guidelines: Autoimmune hepatitisq
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EASL Clinical Practice Guidelines: Autoimmune hepatitisq
EASL Clinical Practice guidelines : Autoimmune hepatitisqEuropean Association for the Study of the Liver IntroductionAutoimmune hepatitis (AIH) was the first liver disease for whichan effective therapeutic intervention, corticosteroid treatment,was convincingly demonstrated in controlled Clinical , 50 years later AIH still remains a major diagnosticand therapeutic challenge. There are two major reasons for thisapparent contradiction: Firstly, AIH is a relatively rare , AIH is a very heterogeneous other rare diseases, Clinical studies are hampered by thelimited number of patients that can be included in trials. Possiblyand more importantly, the interest of the pharmaceutical indus-try to develop effective specific therapies for rare diseases is lim-ited due to the very restricted market for such products. The wideheterogeneity of affected patients and Clinical manifestations ofthe disease limits both diagnostic and further therapeutic s age spectrum is extremely wide, it can affect small infantsand can manifest for the first time in octogenarians.
EASL Clinical Practice Guidelines: Autoimmune hepatitisq European Association for the Study of the Liver⇑ Introduction Autoimmune hepatitis (AIH) was the first liver disease for which
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